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Capastat (capreomycin) Disease Interactions

There are 2 disease interactions with Capastat (capreomycin):

Major

Capreomycin (Includes Capastat) ↔ hearing loss

Severe Potential Hazard, High plausibility. Applies to: Hearing Loss

Capreomycin is potentially ototoxic, both to vestibular and to auditory functions. The risk is greatest in patients receiving large doses for prolonged periods of time. Its use in patients with preexisting auditory impairment must be undertaken with great caution, and the risk of additional cranial nerve VIII impairment should be weighed against the benefits to be derived from therapy. Audiometric measurements and assessment of vestibular function should be performed prior to initiation of therapy with at regular intervals during treatment.

References

  1. "Product Information. Capastat Sulfate (capreomycin)." Dura Pharmaceuticals, San Diego, CA.
Major

Capreomycin (Includes Capastat) ↔ renal dysfunction

Severe Potential Hazard, High plausibility. Applies to: Renal Dysfunction

Renal injury, with tubular necrosis, elevation of the blood urea nitrogen (BUN) or serum creatinine, and abnormal urinary sediment, has been noted with the use of capreomycin. Its use in patients with renal insufficiency must be undertaken with great caution, and the risk of additional renal injury should be weighed against the benefits to be derived from therapy.

References

  1. "Product Information. Capastat Sulfate (capreomycin)." Dura Pharmaceuticals, San Diego, CA.

Capastat (capreomycin) drug interactions

There are 144 drug interactions with Capastat (capreomycin)

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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