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Medical Term:

Wolff-Chaikoff block

Pronunciation: vulf chī′kof

Definition: obstruction of the organic binding of iodine and its incorporation into hormone, caused by large doses of iodine; usually transient, but in large doses in susceptible people, the effect can be prolonged and cause iodine myxedema.

Synonym(s): Wolff-Chaikoff effect

[Louis Wolff; Israel Chaikoff]