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Wiskott-Aldrich syndrome

Pronunciation: wis'kot awl'drich

Definition: an immunodeficiency disorder occurring in male children and characterized by thrombocytopenia, eczema, melena, and susceptibility to recurrent bacterial infections; death occurs from severe hemorrhage or overwhelming infection; X-linked recessive inheritance, caused by mutation in the Wiskott-Aldrich syndrome protein (WASP) on chromosome Xp.

Synonym(s): Aldrich syndrome

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© Copyright 2017 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.
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