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Medical Term:

wire-loop lesion


Definition: thickening of the basement membrane, with fibrinoid staining, of scattered peripheral capillaries in renal glomeruli; characteristic of renal involvement in systemic lupus erythematosus; the appearance of an affected capillary wall resembles a loop used in microbiology.

© Copyright 2016 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.