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white sponge nevus


Definition: an autosomal dominant condition of the oral cavity characterized by soft, white or opalescent, thickened, and corrugated folds of mucous membrane; other mucosal sites are occasionally involved simultaneously; caused by mutation in either the mucosal keratin gene K4 on chromosome 12 or the keratin-13 gene on 17.

Synonym(s): familial white folded dysplasia, oral epithelial nevus

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.