Definition: In prostate cancer, a approach in which treatment of local disease is not performed due to a belief it is not helpful due to the long natural course of the disease. This approach should not be confused with active surveillance (q.v.), in which immediate therapy is postponed in patients deemed at low risk for progression with treatment of localized disease initiated when the patient develops an increased risk of disease progression.
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Examples: glitazone, GI cocktail, etc.