Definition: a complement-fixation test used in the diagnosis of syphilis; originally the “antigen” was an extract of liver from a syphilitic fetus, but later the active substance, referred to as cardiolipin, was found to be present in normal tissues, including heart, and has been identified as a diphosphatidylglycerol.
Synonym(s): Wassermann reaction
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Examples: glitazone, GI cocktail, etc.