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vinblastine sulfate

Pronunciation: vin-blas'ten sul'fat

Definition: A dimeric alkaloid obtained from Vinca rosea. It arrests mitosis in metaphase (although vincristine is more active in this respect) and exhibits greater antimetabolic activity than does vincristine; used in the treatment of Hodgkin disease, choriocarcinoma, acute and chronic leukemias, and other neoplastic diseases; blocks microtubule assembly.

Synonym(s): vincaleucoblastine

Further information

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.

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