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Medical Term:

van Buchem syndrome

Pronunciation: vahn bu'kem


an osteosclerosing skeletal dysplasia, characterized by mandibular enlargement, thickening of the diaphyses and calvaria, and increased serum alkaline phosphatase; autosomal recessive inheritance.

Synonym(s): generalized cortical hyperostosis

© Copyright 2017 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.