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Pronunciation: vak'yu-ol


  1. A minute space in any tissue.
  2. A clear space in the substance of a cell, sometimes degenerative in character, sometimes surrounding an engulfed foreign body and serving as a temporary cell stomach for the digestion of the body.

[Mod. L. vacuolum, dim. of L. vacuum, an empty space]

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.