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vaccinia virus

 

Definition: the poxvirus (genus Orthopoxvirus) used in the immunization of people against variola (smallpox), usually causing a local reaction but sometimes generalized vaccinia, especially in children; the virus is closely related serologically to the viruses of variola and cowpox, but certain differences have been demonstrated that indicate that they are perhaps distinct but closely related strains of a variola-vaccinia-cowpox complex; the lineage of vaccinia virus is uncertain, and it is very unlikely that it descended from Jenner original virus.

Synonym(s): poxvirus officinalis

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© Copyright 2017 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.
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