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uncouplers

Pronunciation: un-kup'lerz

Definition: Substances such as dinitrophenol that allow oxidation in mitochondria to proceed without the usual concomitant phosphorylation to produce ATP; these poisons thus “uncouple” oxidation and phosphorylation.

Synonym(s): uncoupling factors

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© Copyright 2017 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.
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