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Medical Term:


Pronunciation: un-kup'lerz

Definition: Substances such as dinitrophenol that allow oxidation in mitochondria to proceed without the usual concomitant phosphorylation to produce ATP; these poisons thus “uncouple” oxidation and phosphorylation.

Synonym(s): uncoupling factors

© Copyright 2016 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.