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unbalanced translocation


Definition: condition resulting from fertilization of a gamete containing a translocation chromosome by a normal gamete; if this abnormality is compatible with life, the individual would have 46 chromosomes but a segment of the translocation chromosome would be represented three times in each cell and a partial or complete trisomic state would exist.

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.