Definition: a chronic disease of unknown cause characterized by ulceration of the colon and rectum, with rectal bleeding, mucosal crypt abscesses, inflammatory pseudopolyps, abdominal pain, and diarrhea; frequently causes anemia, hypoproteinemia, and electrolyte imbalance, and is also less frequently complicated by peritonitis, toxic megacolon, or carcinoma of the colon.
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Examples: glitazone, GI cocktail, etc.