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Uhthoff symptom

Pronunciation: ut'hof

Definition: a transient temperature-dependent numbness, weakness, or loss of vision. Conduction stops in any nerve if the temperature becomes too elevated. In a damaged nerve, by demyelinization, this shutdown temperature is lowered, and may approach normal body temperature. Transient neurologic dysfunction may then appear with a hot shower, exercise, or fever.

Synonym(s): Uhthoff syndrome

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.