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ubiquitin-protease pathway

 

Definition: pathway in which a small protein cofactor, ubiquitin, couples with protein substrate to catalyze proteolytic destruction by proteases; this pathway is highly selective and tightly regulated and is responsible for protein degradation seen in muscle-wasting diseases.

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.

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