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Tzanck test

Pronunciation: tsahnk

Definition: the examination of fluid from a bullous lesion for Tzanck cells (altered epithelial cells, rounded and devoid of intercellular attachments). The periphery of these cells is basophilic and the nucleus is spheric and enlarged with prominent nucleoli; they are characteristic of lesions due to varicella, herpes zoster, herpes simplex, and pemphigus vulgaris.

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.