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Medical Term:

tubulin-tyrosine ligase


Definition: an enzyme that covalently links a tyrosine to the C-terminal glutamyl residue of tubulin, coupled with the hydrolysis of ATP to ADP and orthophosphate; this is a unique posttranslational modification that may have a significant role in cytoskeletal traffic, design, and stability.

© Copyright 2016 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.