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triosephosphate isomerase

Pronunciation: tri'os-fos'fat i-som'er-as

Definition: An isomerizing enzyme that catalyzes the reversible interconversion of d-glyceraldehyde 3-phosphate and dihydroxyacetone phosphate, a reaction of importance in glycolysis and gluconeogenesis; a deficiency of this enzyme will result in hemolytic anemia and severe neurologic deficits.

Synonym(s): phosphotriose isomerase

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© Copyright 2017 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.
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