Pronunciation: tri'os-fos'fat i-som'er-as
An isomerizing enzyme that catalyzes the reversible interconversion of d-glyceraldehyde 3-phosphate and dihydroxyacetone phosphate, a reaction of importance in glycolysis and gluconeogenesis; a deficiency of this enzyme will result in hemolytic anemia and severe neurologic deficits.
Synonym(s): phosphotriose isomerase
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Examples: glitazone, GI cocktail, etc.