Definition: Descriptive term applied to the enzymes catalyzing, among others, the following reactions involving sulfur-containing compounds: 1) cystathionine ? cysteine + a-ketobutyrate + NH3 (cystathionine ?-lyase); 2) cystathionine ? homocysteine + pyruvate + NH3 (cystathionine ß-lyase); 3) cystine ? thiocysteine + pyruvate + NH3 (cystathionine ?-lyase); 4) cystathionine ? serine + homocysteine (cystathionine synthase).
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Examples: glitazone, GI cocktail, etc.