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transposable element

 

Definition: a DNA sequence that can move from one location in the genome to another; the transposition event can involve both recombination and replication, producing two copies of the moving piece of DNA; the insertion of these DNA fragments can disrupt the integrity of the target gene, possibly causing activation of dormant genes, deletions, inversions, and a variety of chromosomal aberrations.

See Also: transposon

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© Copyright 2017 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.
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