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Medical Term:

toxic epidermal necrolysis


a syndrome in which a large portion of the skin becomes intensely erythematous with epidermal necrosis and peels off in the manner of a second-degree burn, often simultaneous with the formation of flaccid bullae, resulting from drug sensitivity or of unknown cause; the level of separation is subepidermal, unlike staphylococcal scalded skin syndrome in which there is subcorneal change.

Synonym(s): Lyell syndrome

© Copyright 2017 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.