Skip to Content


Pronunciation: tok-se'me-a


  1. Clinical manifestations observed during certain infectious diseases, assumed to be caused by toxins and other noxious substances elaborated by the infectious agent; in certain infections by gram-negative bacteria, endotoxins probably play a role when the bacterial cell wall breaks down, releasing a complex lipopolysaccharide; however, the role of other bacterial substances is unclear, except in the case of the specific exotoxins such as those of diphtheria and tetanus.
  2. The clinical syndrome caused by toxic substances in the blood.
  3. A lay term referring to the hypertensive disorders of pregnancy.

Synonym(s): toxicemia

[G. toxikon, poison, + haima, blood]

Disclaimer: This site is designed to offer information for general educational purposes only. The health information furnished on this site and the interactive responses are not intended to be professional advice and are not intended to replace personal consultation with a qualified physician, pharmacist, or other healthcare professional. You must always seek the advice of a professional for questions related to a disease, disease symptoms, and appropriate therapeutic treatments.
© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.