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topoisomerase

Pronunciation: to'po-i-som'er-as

Definition: A type of enzyme converting (isomerizing) one topologic version of DNA into another; acts by catalyzing the breakage and reformation of DNA phosphodiester linkages.

[topo- + isomerase]

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.

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