An herb of South American origin, Nicotiana tabacum, which has large ovate to lanceolate leaves and terminal clusters of tubular white or pink flowers. Tobacco leaves contain 2–8% of nicotine and are the source of smoking and chewing tobacco or snuff. Tobacco smoke contains nicotine, carbon monoxide (4%), nitric oxide, and numerous aromatic hydrocarbons and other substances known to be carcinogens, including benzo[a]pyrene, ß-naphthylamine, and nitrosamines.
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Examples: glitazone, GI cocktail, etc.