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thyroid peroxidase


Definition: thyroid oxidoreductase that catalyzes incorporation of iodide to tyrosine residues in the production of thyroxine, in a process termed organification (q.v.); deficiency of this enzyme leads to a loss of the iodotyrosine derivatives and iiodine from the thyroid and results in goiter.

Synonym(s): iodide peroxidase, iodinase, iodotyrosine deiodase

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.