- An enzyme (proteinase), formed in shed blood, that converts fibrinogen into fibrin by hydrolyzing peptides (and amides and esters) of l-arginine; formed from prothrombin by the action of prothrombinase (factor Xa, another proteinase).
- A sterile protein substance prepared from prothrombin of bovine origin through interaction with thromboplastin in the presence of calcium; causes clotting of whole blood, plasma, or a fibrinogen solution; used as a topical hemostatic for capillary bleeding with or without fibrin foam in general and plastic surgical procedures.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.
Search Stedman's Medical Dictionary
Examples: glitazone, GI cocktail, etc.