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Definition: An agonist at ?-aminobutyric acid (GABA) type A receptors. Unlike other agonists of this type, on systemic administration THIP penetrates the blood-brain barrier and is used as a pharmacologic tool to explore GABA receptor function in the brain and spinal cord.

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.