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thiaminase

Pronunciation: thi-am'i-nas

Definition:

  1. An enzyme present in raw fish that destroys thiamin and may produce thiamin deficiency in animals on a diet largely composed of raw fish.
  2. A hydrolase cleaving thiamin into a pyrimidine moiety (2-methyl-4-amino-5-hydroxymethylpyrimidine) and a thiazole moiety (4-methyl-5-(2'-hydroxyethyl)thiazole); the pyrimidine moiety may appear in the urine as pyramin.

Synonym(s): thiaminase II

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© Copyright 2017 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.
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