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thecoma

Pronunciation: the-ko'ma

Definition: A neoplasm derived from ovarian mesenchyme, consisting chiefly of spindle-shaped cells that frequently contain small droplets of fat; gross features generally resemble those of a granulosa cell tumor, firm, yellow, encapsulated mass, ordinarily about 10 cm or less in diameter, but it tends to be less malignant; it may form considerable quantities of estrogens, thereby resulting in precocious development of secondary sexual features in prepubertal girls, or hyperplasia of the endometrium in older patients.

Synonym(s): theca cell tumor

[G. theke, box (theca), + -oma, tumor]

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.

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