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thalassemia

Pronunciation: thal'a-se'me-a, tha-las-a-ne'me-a

Definition: Any of a group of inherited disorders of hemoglobin metabolism in which there is impaired synthesis of one or more of the polypeptide chains of globin; several genetic types exist, and the corresponding clinical picture may vary from barely detectable hematologic abnormality to severe and fatal anemia.

[G. thalassa, the sea, + haima, blood]

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.

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