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Pronunciation: tet'ra-gas'trin


  1. A tetrapeptide (Trp–Met–Asp–Phe–NH2) used to test the secretion of digestive juice.
  2. A pterin derivative that is a required cofactor for a number of enzymes; in the conversion of l-phenylalanine to l-tyrosine; the inability to synthesize tetrahydrobiopterin is associated with forms of malignant hyperphenylalaninemia.

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.