Definition: a slender, compact fiber bundle that connects the amygdala (amygdaloid body) with the hypothalamus and other basal forebrain regions. Originating from the amygdala, the bundle passes first caudad in the roof of the temporal horn of the lateral ventricle; it follows the medial side of the caudate nucleus forward in the floor of the ventricle's central part (or body) until it reaches the interventricular foramen, in the posterior wall of which it curves steeply down to enter the hypothalamus, with fibers passing both rostral and caudal to the anterior commissure. Coursing caudally in the medial part of the hypothalamus, the bundle terminates in the anterior and ventromedial hypothalamic nuclei.
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