Definition: Any member of a group of polypeptides, widely scattered in vertebrate and invertebrate tissues, which have in common four of the five terminal amino acids: Phe–Xaa–Gly–Leu–Met–NH2; pharmacologically, they all cause hypotension in mammals, contraction of gut and bladder smooth muscle, and secretion of saliva.
[G. tachys, swift, + kineo, to move, + -in]
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Examples: glitazone, GI cocktail, etc.
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