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Tac antigen


Definition: an antigenic determinant of the human interleukin 2 receptor that is identified by a murine monoclonal antibody, anti-Tac. Binding of this antigen with antibodies to TAC prevents the proliferation of T cells, which is normally stimulated by binding interleukin-2.

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.