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T lymphocyte

 

Definition: a lymphocyte formed in the bone marrow from which it migrates to the thymic cortex to become an immunologically competent cell; T lymphocytes have long lifespans (months to years) and are responsible for cell-mediated immunity; T lymphocytes form rosettes with sheep erythrocytes and differentiate and divide in the presence of transforming agents (mitogens); T lymphocytes have characteristic T cell receptor-CD3 complexes as surface markers and may be further categorized by function, such as helper and cytotoxic.

Synonym(s): T cell

See Also: B lymphocyte

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© Copyright 2017 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.
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