Skip to Content

ß-hydroxy-ß-methylglutaryl- synthase


Definition: an enzyme in mitochondria that catalyzes the reaction of acetyl-CoA with acetoacetyl-CoA and water to form (S)-ß-hydroxy-ß-methylglutaryl-CoA and coenzyme A, a step required for both ketogenesis and steroidogenesis to occur.

Disclaimer: This site is designed to offer information for general educational purposes only. The health information furnished on this site and the interactive responses are not intended to be professional advice and are not intended to replace personal consultation with a qualified physician, pharmacist, or other healthcare professional. You must always seek the advice of a professional for questions related to a disease, disease symptoms, and appropriate therapeutic treatments.
© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.