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Medical Term:

ß-hydroxy-ß-methylglutaryl- synthase


an enzyme in mitochondria that catalyzes the reaction of acetyl-CoA with acetoacetyl-CoA and water to form (S)-ß-hydroxy-ß-methylglutaryl-CoA and coenzyme A, a step required for both ketogenesis and steroidogenesis to occur.

© Copyright 2017 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.