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ß-hydroxy-ß-methylglutaryl- reductase


Definition: an enzyme that catalyzes the rate-limiting step of cholesterol biosynthesis: ß-hydroxy-ß-methylglutaryl-CoA + 2NADPH + 2H+ ? (R)-mevalonate + 2NADP+ + CoA.

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.