The presence in the spinal cord of longitudinal cavities lined by dense, gliogenous tissue, which is not caused by vascular insufficiency. Syringomyelia is marked clinically by pain and paresthesia, followed by muscular atrophy of the hands and analgesia with thermoanesthesia of the hands and arms, but with the tactile sense preserved; later marked by painless whitlow, spastic paralysis in the lower extremities, and scoliosis of the lumbar spine. Some cases are associated with low grade gliomas or vascular malformations of the spinal cord.
[syringo- + G. myelos, marrow]
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Examples: glitazone, GI cocktail, etc.