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survivin

Pronunciation: sur-vi'v'in

Definition: Human gene encoding a unique IAP apoptosis inhibitor. Survivin is present in fetal tissues, but is undetectable in adult tissues. It is, however, expressed in transformed cell lines and in the most common types of human cancer (lung, colon, pancreas, prostate, breast) as well as in high-grade non-Hodgkin lymphomas.

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.

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