Definition: the development of preeclampsia in a patient with chronic hypertensive vascular or renal disease; when the hypertension antedates the pregnancy as established by previous blood pressure recordings, a rise in the systolic pressure of 30 mmHg or a rise in the diastolic pressure of 15 mmHg and the development of proteinuria or edema, or both, are required during pregnancy to establish the diagnosis.
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Examples: glitazone, GI cocktail, etc.