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sulfadiazine

Pronunciation: sul'fa-di'a-zen

Definition: One of a group of diazine derivatives of sulfanilamide, the pyrimidine analogue of sulfapyridine and sulfathiazole; one of the components of the triple sulfonamide mixture. It is an inhibitor of bacterial folic acid synthesis, which has been highly effective against pneumococcal, staphylococcal, and streptococcal infections, against infections with Escherichia coli and Klebsiella pneumoniae, and in acute gonococcal arthritis; sulfadiazine sodium has the same uses.

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.

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