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Medical Term:

succinyl-CoA synthetase


  1. a ligase reversibly reacting succinate and CoA with ATP to produce ADP, inorganic phosphate, and succinyl-CoA;
  2. a similar synthetase, but one able to use itaconate as well as succinate and GTP (or ITP) in place of ATP; a part of the tricarboxylic acid cycle.

Synonym(s): succinate:CoA ligase, succinate:CoA ligase, succinic thiokinase

© Copyright 2017 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.