subtilisin

Pronunciation: sub-til'i'sin

Definition: A proteinase produced by Bacillus subtilis and other species, similar to the serine proteinases of other molds and bacteria; it catalyzes the hydrolysis of a few specific peptide bonds in certain proteins, converting chymotrypsinogen to chymotrypsin and ovalbumin to plakalbumin in this manner, and cleaves pancreatic ribonuclease into S-peptide and S-protein.

Synonym(s): subtilopeptidase

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.

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