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Pronunciation: sub'strat


  1. The substance acted on and changed by an enzyme; the reactant considered to be attacked in a chemical reaction.
  2. That on which an organism lives or grows (the substrate on which microorganisms and cells grow in cell culture).

[L. sub-sterno, pp. -stratus, to spread under]

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.