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streptomycin

Pronunciation: strep'to-mi'sin

Definition: An antibiotic agent obtained from Streptomyces griseus that is active against the tubercle bacillus and a large number of gram-positive and gram-negative bacteria; also used in the form of dihydrostreptomycin (aldehyde of streptomycin reduced to CH2OH). It is used virtually exclusively in the treatment of tuberculosis; toxicity includes eighth cranial nerve damage leading to deafness and/or vestibular dysfunction.

Synonym(s): streptomycin A

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.

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