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steroid 5a-reductase

 

Definition: an enzyme that uses NADPH to reduce certain steroids (the conversion of testosterone to dihydrotestosterone); a deficiency of this enzyme is associated with a form of male pseudohermaphroditism in which genetic males have male genitals as well as female external genitalia.

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© Copyright 2017 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.
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