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Medical Term:

sphingomyelin phosphodiesterase

Pronunciation: sfing'go-mi'e-lin fos'fo-di-es'ter-as

Definition: An enzyme catalyzing hydrolysis of sphingomyelin to N-acylsphingosine (a ceramide) and phosphocholine; a deficiency of this enzyme is associated with type I Niemann-Pick disease.

Synonym(s): sphingomyelinase

© Copyright 2016 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.
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