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Pronunciation: so'ma-to-stat'in

Definition: A tetradecapeptide capable of inhibiting the release of somatotropin by the anterior lobe of the pituitary gland; somatostatin has a short half-life; it also inhibits the release of insulin, glucagon, and gastrin. Used in the treatment of acromegaly, gigantism, and pancreatic tumors.

Synonym(s): growth hormone–inhibiting hormone, somatotropin release-inhibiting factor, somatotropin release-inhibiting hormone

[somatotropin + G. stasis, a standing still, + -in]

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.