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somatomedin

Pronunciation: so'ma-to-me'din

Definition: One of several peptides; somatomedin peptide (MW about 4,000), also called insulinlike growth factor II, is synthesized in the liver and probably in the kidney; it is capable of stimulating certain anabolic processes in bone and cartilage, such as synthesis of DNA, RNA, and protein (including chondromucoprotein), and the sulfation of mucopolysaccharides; secretion and biologic activity of somatomedin is known to depend on somatotropin.

[somato, tropin + mediator + -in]

See Also: insulinlike growth factor

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© Copyright 2017 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.
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